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Table 3 Significant important genes distinguishing genotoxicity and cytotoxicity

From: Graph ranking for exploratory gene data analysis

Gene ID Gene Name Description
YGR180C* RNR4 Ribonucleotide-diphosphate reductase (RNR)
YLR178C* TFS1 Carboxypeptidase Y inhibitor
YDR001C* NTH1 Neutral trehalase, degrades trehalose
YJL178C* ATG27 Type I membrane protein
YMR090W*   unkown function
YGL063W PUS2 Mitochondrial tRNA:pseudouridine synthase
YGR036C CAX4 Dolichyl pyrophosphate (Dol-P-P) phosphatase
YHL028W WSC4 ER membrane protein
YIL149C MLP2 Myosin-like protein associated with the nuclear envelope
  1. Genes selected in this table are capable of discriminating between genotoxic and cytotoxic agents. They behave similarly within group but totally different between groups. Genes with * are over-expressed for genotoxic treatments but down-regulated for cytotoxic components. Genes without * are induced for cytotoxic stress but repressed for genotoxic stress.
  2. Genes with * are over-expressed under treatment of genotoxic stress but under-regulated for cytotoxic stress. Genes without * are induced for cytotoxic but repressed for genotoxic compounds.