Figure 3
From: Integrating phenotype and gene expression data for predicting gene function
Predicting transfer to annotations to genes. When considering whether an annotation a should be assigned to gene g, the total similarity of each gene with annotation a to gene g is computed. If the total similarity is greater than the upper threshold, the annotation is assigned. If the total similarity is less than the lower threshold, the annotation is never assigned. For genes with a total similarity greater than the lower threshold but less than the upper threshold, linear interpolation is used to determine where the similarity falls relative to the two thresholds. If the interpolated similarity is above a predefined cutoff, the annotation is assigned. The pink area indicates similarity values for which the annotation will be transferred.