Figure 3

GO Annotation Quality ( GAQ ) score. GAQ Scores were calculated for the existing GO annotation on the array and the GO annotation available after we added the additional annotations described in this paper. GAQ Scores are calculated exactly as described previously [22]. Briefly, GAQ score quantitatively measures GO quality, which includes breadth of GO annotation, the level of detail of annotation (depth), and the type of evidence used to make the annotation. Additional GO improved the meanGAQ score 16-fold, from 1.6 for the pre-existing GO to 26.7 for the completed or additional GO. meanGAQ score for each ontology is shown as well. Cellular component increased 11-fold, from 0.4 to 4.5, biological process increased 16-fold, from 0.5 to 8.1, and molecular function increased 18-fold, or from 0.7 to 13.2.