Figure 1

Statistical analysis of the 41 PKA pathway-encoding genes expression in normal and transformed samples. 81 transcriptional profiles from normal tissues and from the NCI60 cancer cell line collection, were recovered from the GEO database. After normalization (see Methods), the expression values of 41 PKA pathway-encoding genes were used to perform an ANOVA analysis (p-value 0.0001) to evaluate the statistical significance of the differences between normal and transformed samples. IQR: Interquartile Range. Outliers are also shown.