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Table 2 Gene expression profiling datasets of NCI60 cell lines and normal tissues analyzed in this study

From: Data recovery and integration from public databases uncovers transformation-specific transcriptional downregulation of cAMP-PKA pathway-encoding genes

Reference

Tissue of origin

Number of transcriptional profiles

GEO Number

[31]

NCI60 cells

60

GSE5949

 

Breast

0

-

[106]

CNS

2

GSE96

[107]

Colon

4

GSE6731

[108]

Blood

4

GSE1402

[106]

Lung

2

GSE96

 

Skin

0

-

[106]

Ovary

3

GSE96

[106]

Prostate

3

GSE96

[106]

Kidney

3

GSE96

  1. Gene expression profiles retrieved from the GEO Database. Dataset A (60 profiles) is made up of the NCI60 cell lines [31]. Dataset B (13 profiles) is a subset of transcriptional profiles of a diverse array of tissues, organs, and cell lines from a normal human physiological state [106]. Dataset C (4 profiles) encompasses the normal human adult samples derived from colonoscopic biopsy present in a database comprising samples of patients with Crohn's disease or ulcerative colitis [107]. Dataset D (4 profiles) contains normal control samples present in a database containing transcriptional profiles of peripheral blood mononuclear cells (PBMC) obtained by juvenile arthritis patients and healthy controls [108].