Figure 2From: Modulation of p53 binding to MDM2: computational studies reveal important roles of Tyr100Superimposed structures of 'open' (salmon red), 'closed' (yellow) and 'apo' (purple) states of MDM2. The residues L54, H96 and Y100 have been shown in sticks for all conformations and the residue names have been labeled for the apo-state. The Y100 is deeply buried in the apo-state.Back to article page