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Table 3 B↔C comparison and modified result.

From: Mining metastasis related genes by primary-secondary tumor comparisons from large-scale databases

Class

Gene

B vs. C

Liver viability

Difference

Liver and metastasis dependency

B↔C only

COLEC11

3.95

2.45

1.49

Liver up-regulated

 

NRBP2

3.29

3.57

-0.28

Liver up-regulated

 

FGG

3.26

3.81

-0.55

Liver specific

 

ART4

3.19

2.08

1.10

Liver specific

 

LBP

3.15

3.44

-0.28

-

 

GADD45B

3.15

2.82

0.33

-

 

HP /// HPR

3.11

3.69

-0.58

Liver specific

 

ALB

3.088

3.80

-0.71

Liver specific

 

C10ORF11

3.06

2.25

0.80

-

 

GCKR

3.03

3.40

-0.36

-

Modified with liver viability

MGC16121

2.43

-1.39

3.83

Unknown

 

HS3ST2

2.34

-0.39

2.74

-

 

DHRS12

2.11

-0.43

2.54

-

 

MSR1

2.07

-0.33

2.41

Inflammation

 

DNASE1

2.10

-0.23

2.33

-

 

MARCO

2.86

0.55

2.31

Macrophage receptor

 

SPAG4

2.18

-0.10

2.28

-

 

INMT

2.93

0.71

2.22

-

 

AOAH

2.45

0.26

2.19

Metastasis related

 

EPO

2.20

0.14

2.05

Cancer and metastasis

  1. The result of a naive comparison between a metastatic tumor (B) and a primary tumor (C) is shown in the upper row. This comparison is expected to represent not only metastatic ability but also liver environmental viability. Normalizing with the liver environmental viability related genes successfully eliminated many genes not selected for metastatic characteristics in the result of our methods (lower row).