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Figure 4 | BMC Bioinformatics

Figure 4

From: Extraction of human kinase mutations from literature, databases and genotyping studies

Figure 4

Evaluation of classifying induced mutation mentions and natural variants. A. Box plot of the sentence classifier scores for Natural Variant (NV) annotated mutations in SwissProt and a random subset of sentence scores from mutation mentioning sentences. B. Example cases of mutation mentions corresponding to natural variant and induced mutations. C. Example features used by the sentence classifier for the positive class (Natural Variant) and the Negative class (Figure D, induced mutation). E and F Manual classification result for 50 randomly selected mutation mentioning sentences for classifier score intervals. (1) Score above 4, (2) score range of 4-3, (3) score range 3-2, (4) score range 2-1, (5) score range 1-0, (6) score range 0 to minus 1, (7) score range from minus 1 to minus 2, (8) score range from minus 2 to minus 3, (9) score range below minus 3. Positive scores correspond to mutations classified as natural variant, negative scores correspond to mutations classified as induced/mutagenesis.

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