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Figure 2 | BMC Bioinformatics

Figure 2

From: Improved mutation tagging with gene identifiers applied to membrane protein stability prediction

Figure 2

Improvement of gene normalization. Example for gene name normalization with the help of mutation mining. Initially, our gene normalizer proposed the human gene CCP as its context fits the text best (abstract not fully shown). However, when comparing the recognized mutation at position 191 with the sequences of all three candidates, only CCP in yeast contains the wild-type tryptophan at the specified position (PDB entry). After checking the full text of this publication, we found that CCP indeed refers to the gene in Saccharomyces cerevisiae.

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