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Table 1 Mutation databases: Most of available mutation databases focus on mutations from human, or specific protein families (e.g. G protein-coupled receptors). Some lack well-defined information on mutant phenotypes and only few link to interaction data. Half of the databases also contain data retrieved by text mining methods.

From: Improved mutation tagging with gene identifiers applied to membrane protein stability prediction

 

Species

SNPs

Protein mutations

Diseases

Phenotypes

Interactions

Text Mining

OMIM [5]

human

+

+

+

+

+

-

HGMD [8]

human

+

+

+

+

-

+

UniProtKB [6]

various

-

+

-

+

-

+

HGVbase [10]

human

+

-

+

+

-

-

HapMap [41]

human

+

-

-

-

-

-

dbSNP [42]

44

+

+

-

+

-

-

MutDB [11]

human

+

+

-

-

+

-

GPCRDB [43]

18

-

+

-

+

-

-

GPCR NaVa [13]

human

+

+

+

+

-

-

CoagMDB [44]

human

+

+

-

+

-

+

OSIRIS [45]

human

+

-

+

-

-

+

PolySearch [46]

various

+

+

+

-

+

+