Table 6 Overall F1 measure of the entire classification. The global F1 measure of the classification problem is computed by two different types of averages: micro-average and macro-average. In micro-averaging, the F1 measure is calculated globally over all categories, while in macro-averaging, F1 is computed locally over each category first, and then the average over all categories is taken.

From: Annotation of protein residues based on a literature analysis: cross-validation against UniProtKb