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Figure 10 | BMC Bioinformatics

Figure 10

From: From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways

Figure 10

Workflow of the data integration process. 1) Data on mutations and sequence variants is gathered from UniProt. 2) The disease association mapping to OMIM is obtained from UniProt, if available. 3) A mapping of UniProt and Entrez Gene ids is created. 4) The annotation to dbSNP, which is in part provided by UniProt is extended. 5) Further annotations to GO ontology are obtained by NER. 6) Cytoscape node attribute files are created from the integrated data that is stored in a SQL database. 7) The annotated network is visualized in Cytoscape.

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BMC Bioinformatics

ISSN: 1471-2105

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