Figure 8From: From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathwaysDynamic and dose response of the ErbB signalling pathway in the presence of mutated MEK1. Simulation of Akt activation in response to simulatenous EGF and HGR stimulation. (A) EGF: 10 nM, HGR increasing. (B) HGR 10 n M, EGF increasing. Responses were obtained and normalized as described in [35].Back to article page