Figure 2From: MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in diseaseNormalized distribution of prioritized variation across mtDNA. The graph shows a gene-wise comparison of reported (ratioR) and high scoring (ratioP) variations normalized for gene length. It can be seen that there is a bias towards tRNA genes which are also reported hot spots in many mitochondrial diseases.Back to article page