Figure 3
From: Analysis of AML genes in dysregulated molecular networks
The enrichment of AML mutation genes in subnetworks. 18 out of 62 AML genes (29.03%) were found in 269 subnetworks including 859 genes, and their enrichment was significant (p-value P = 7.14e-6) through the hypergeometric test (the probability of 18 AML genes out of all 62 are found in the subnetworks including total 859 genes out of 9142 genes in the whole network). In contrast, only two AML genes (FLT3, JAK3) (3.23%) were found among 859 top differentially expressed genes in their mRNA levels (P = 0.04)