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Table 1 AML mutation genes in subnetworks

From: Analysis of AML genes in dysregulated molecular networks

Genes Number of Subnetworks Degree DES+
JAK3* 110 32 2.73
KIT 43 54 1.97
EVI1 16 7 -1.27
CREBBP 14 209 1.5
EP300 7 216 2.36
BCR 2 32 1.41
FLT3** 2 11 3.58
NSD1 2 6 1.14
PTPN11 1 109 -1.07
JAK2 1 87 N/A
PDGFRB 1 56 -0.33
NPM1 1 33 -0.37
RUNX1 1 22 0.68
GATA2 1 20 1.58
PICALM 1 8 0.44
FNBP1 1 7 2.05
RPL22 1 3 1.08
TRIP11 1 2 -1.29
  1. +DES means the degree of change in its mRNA level for each gene.
  2. Genes with the absoluteDES ranked within top 5% are marked with **, and genes within top 10% are marked with *.