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Table 1 AML mutation genes in subnetworks

From: Analysis of AML genes in dysregulated molecular networks

Genes

Number of Subnetworks

Degree

DES+

JAK3*

110

32

2.73

KIT

43

54

1.97

EVI1

16

7

-1.27

CREBBP

14

209

1.5

EP300

7

216

2.36

BCR

2

32

1.41

FLT3**

2

11

3.58

NSD1

2

6

1.14

PTPN11

1

109

-1.07

JAK2

1

87

N/A

PDGFRB

1

56

-0.33

NPM1

1

33

-0.37

RUNX1

1

22

0.68

GATA2

1

20

1.58

PICALM

1

8

0.44

FNBP1

1

7

2.05

RPL22

1

3

1.08

TRIP11

1

2

-1.29

  1. +DES means the degree of change in its mRNA level for each gene.
  2. Genes with the absoluteDES ranked within top 5% are marked with **, and genes within top 10% are marked with *.