Figure 4
From: SplicerAV: a tool for mining microarray expression data for changes in RNA processing
SplicerAV Index of ARHGEF7 is associated with breast cancer survival. Panel A. Schematic representation of ARHGEF7 isoforms A, B and C, with regions interrogated by probesets that increase shown as Probesets Up 1 and 2 (red arrows), and the region which decreases denoted as Probeset Down (blue arrow). Panel B. The fraction of patients surviving in each cohort (vertical axis) is shown over time in years (horizontal axis) as a function of individual probeset expression or SplicerAV index. Survival of patients in the top (red line) and bottom (blue line) 50th percentile are plotted by individual probeset expression (Down, UP1, and UP2) and the SplicerAV index within the Miller (left) and Pawitan (right) cohorts. Results of two-tailed logrank tests of survival are shown, with asterisks indicating significance at the .05 (large asterisk) and .10 (small asterisk) levels.