Figure 6
From: SplicerAV: a tool for mining microarray expression data for changes in RNA processing
A six isoform signature provides improved prediction of breast cancer survival compared to individual isoforms. The fraction of patients surviving in each cohort (vertical axis) is shown over time in years (horizontal axis) as a function of individual probeset expression or SplicerAV index. Survival of patients in the top (red line) and bottom (blue line) 50th percentile are plotted by the SplicerAV index for six genes; EIF4E2 (A), ARHGEF7 (B), SLC28A10 (C), PDXK (D), TncRNA (E), MAPKAP1 (F) for the Miller (left) and Pawitan (right) cohorts. Patients survival stratified by a low (0-1), intermediate (2-4), and high (5-6) number of poor prognostic events is shown in panel G.