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Table 2 SplicerAV predicts oncogene-induced changes in isoform specific mRNA levels.

From: SplicerAV: a tool for mining microarray expression data for changes in RNA processing

  Unique Expressed Genes SplicerAV Predictions (P < .01)  
GFP vs. Total Multi-probeset Genes Alt. Processed Genes Genes with Splice Score > 0 Significant Gene Ontologies
HRAS 7227 2185 645 212 mRNA splicing (12)
Complement med immunity (3)
G-protein mediated signaling (10)
SRC 7007 2015 291 119 Transcription Elongation (2)
mRNA splicing (7)
CTNNB1 7023 2019 159 54 mRNA processing factors (4)
E2F3 7313 2139 187 45 Cell surface receptor signal (10)
G-protein mediated signaling (6)
Mesoderm development (6)
Cell structure and motility (11)
pre-mRNA splicing (5)
Granulocyte-mediate immunity (2)
MYC 7081 2040 115 12 ---
  1. The total number of unique genes expressed above background, targeted by multiple probesets, predicted to undergo changes in alternative processing, or those predicted to undergo ideal changes are shown in their respective columns for each oncogene (see text). Significantly enriched (p ≤ .05) biological processes or molecular functions of these genes are shown in order of decreasing significance. The number of genes in each GO category is shown in parentheses.