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Table 4 Isoform changes in gene expression significantly associated with patient outcomes in both validation datasets.

From: SplicerAV: a tool for mining microarray expression data for changes in RNA processing

SplicerAV Predictions

Association with Survival

Gene Symbol†

Isoform Probeset

Hypothesis

Miller

Pawitan

ARHGEF7

202548_s_at

DOWN

*0.009

*0.008

DPP7

241973_x_at

DOWN

*0.001

*0.007

EIF4E2

209393_s_at

UP

**0.002

*0.003

MAPKAP1

222426_at

DOWN

*0.019

*0.003

SLC28A10

230448_at

UP

*0.007

0.032

PDXK

202671_s_at

UP

**0.001

0.025

POLI

238992_at

UP

0.037

0.052

SFPQ

201585_s_at

UP

0.062

0.041

SIVA1

203489_at

UP

*0.005

0.075

SSU72

223051_at

UP

*0.018

*0.007

TFDP2

203588_s_at

UP

0.054

*0.008

TIMP2

231579_s_at

DOWN

**0.001

0.056

TncRNA

234989_at

UP

**0.001

0.034

WDFY3

212606_at

UP

0.049

*0.010

WDR26

224897_at

UP

**0.001

0.049

  1. †For genes possessing multiple significant SplicerAV Indices, only one isoform is shown.
  2. *Significant association with survival (p < .01), one sided log rank test
  3. ** Significant association with survival (p < .001), one sided log rank test