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Table 4 Isoform changes in gene expression significantly associated with patient outcomes in both validation datasets.

From: SplicerAV: a tool for mining microarray expression data for changes in RNA processing

SplicerAV Predictions Association with Survival
Gene Symbol† Isoform Probeset Hypothesis Miller Pawitan
ARHGEF7 202548_s_at DOWN *0.009 *0.008
DPP7 241973_x_at DOWN *0.001 *0.007
EIF4E2 209393_s_at UP **0.002 *0.003
MAPKAP1 222426_at DOWN *0.019 *0.003
SLC28A10 230448_at UP *0.007 0.032
PDXK 202671_s_at UP **0.001 0.025
POLI 238992_at UP 0.037 0.052
SFPQ 201585_s_at UP 0.062 0.041
SIVA1 203489_at UP *0.005 0.075
SSU72 223051_at UP *0.018 *0.007
TFDP2 203588_s_at UP 0.054 *0.008
TIMP2 231579_s_at DOWN **0.001 0.056
TncRNA 234989_at UP **0.001 0.034
WDFY3 212606_at UP 0.049 *0.010
WDR26 224897_at UP **0.001 0.049
  1. †For genes possessing multiple significant SplicerAV Indices, only one isoform is shown.
  2. *Significant association with survival (p < .01), one sided log rank test
  3. ** Significant association with survival (p < .001), one sided log rank test