Skip to main content

Table 2 Mutation positions for selected oncogenes

From: Statistical method on nonrandom clustering with application to somatic mutations in cancer

Gene

Position (#of mutations)

BRAF(766 aa)

464(1), 466(2), 469(4), 581(1),

596(2), 597(2), 600(60), 601(2)

KRAS(188 aa)

12(99), 13(32), 22(1), 23(1), 61(6),

117(1), 146(10)

CTNNB1 (781 aa)

6(1), 33(3), 34(2), 37(3), 41(2), 45(2)

PIK3CA(1068 aa)

88(3), 111(3), 118(1), 124(1), 345(1),

449(1), 453(1), 539(1), 542(5),

545(20), 546(2), 549(1), 1023(1),

1025(1), 1047(21), 1049(1), 1066(1)

  1. The number of mutations for each position is shown in parenthesis, positions within clusters from Table 1 are highlighted in bold, and CpG positions are underlined.