Figure 4From: Mathematical model for empirically optimizing large scale production of soluble protein domainsSoluble fragments for individual domains and cleavage sites. (a) Fractions of soluble fragments for individual domains. The horizontal axis represents the ratio of soluble fragments to assessed fragments for each of the 24 analyzable domains. (b) Distribution of the cleavage sites yielding soluble/insoluble fragments. The numbers of soluble and insoluble fragments are shown by white and dark gray bars, respectively. The N- (upper panel) and C-terminal (bottom panel) cleavage sites of the fragments are classified into sites 0-4, as defined in Figure 2b.Back to article page