Figure 2

Heatmap of Drosophilid miRNAs. This figure was generated from a presence/absence matrix, it is color coded to illustrate the effect of mapping using MapMi in the overall view of miRNAs in the species under analysis. Dark purple corresponds to an overlap between MapMi predictions and miRBase annotation. Blue indicates miRNAs that are only present in MapMi, while green indicates miRNAs that are on miRBase but are missing from the MapMi predictions. Bias towards model organisms is readily apparent in this view. It is also clear from the image that MapMi is complementing miRBase in a way that is broadly coherent with the expected evolution of miRNAs across the metazoan lineage. The different species are ordered respecting their phylogenetic relationships, as present in the NCBI taxonomy.