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Table 6 Statistical Analysis of the Improvement in Rank

From: Indirect two-sided relative ranking: a robust similarity measure for gene expression data

Search Size:

10

20

30

40

50

60

70

80

90

Therapuetic Use

         

analgesic

0.136

0.087

0.041

0.020

0.001

2.0E-04

0.004

0.001

0.002

anti-convulsant

0.811

0.529

0.932

0.636

0.918

0.856

0.478

0.481

0.512

anti-inflammatory

0.151

0.040

0.034

0.033

0.002

0.001

0.003

0.002

0.004

anti-neoplastic

0.412

0.842

0.943

0.928

0.577

0.804

0.919

0.909

0.779

anti-proliferative

0.148

0.553

0.778

0.659

0.987

0.881

0.942

0.837

0.837

anti-psychotic (neurole

0.905

0.852

0.686

0.674

0.529

0.129

0.063

0.024

0.006

cardiovascular agent

0.647

0.267

0.496

0.496

0.540

0.795

0.984

0.801

0.687

immunosuppressive agent

0.047

0.664

0.642

0.550

0.525

0.525

0.554

0.323

0.323

tranquilizer

1.000

0.580

0.579

0.921

0.665

0.619

0.413

0.290

0.159

  1. A sensitivity analysis using multiple paired t-tests was performed to analyze the difference in the rank of true positives returned by the direct and indirect method at different search thresholds for rank k. Each cell contains the respective probability. All significant (P < .05) findings are confirmed to be in favor of the indirect method.