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Figure 6 | BMC Bioinformatics

Figure 6

From: The ancient history of the structure of ribonuclease P and the early origins of Archaea

Figure 6

Phylogenomic analysis of domain structure and the age of RPPs. A universal tree of protein architecture was reconstructed from a genomic census of protein domain structure at FSF level of structural classification and RPPs of known structure were traced in the tree. The three evolutionary epochs of the protein world are colored with different shades and are overlapped to the trees, following definitions described in Wang et al. [37]. Terminal leaves are not labeled in the tree since they would not be legible. Branches in red delimit the birth of architectures after the appearance of the first architecture unique to a superkingdom (dashed line). Leaves corresponding to RPP FSFs are indicated and labeled using SCOP nomenclature. The inset shows a representative structure of the FSF architecture d.14.1.

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