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Figure 5 | BMC Bioinformatics

Figure 5

From: Knowledge-guided gene ranking by coordinative component analysis

Figure 5

The identified Notch pathway including several growth factors, transcription factors and oncogenes. Some of the members (e.g., NOTCH3, JAG1, JAG2 and SOX2) are known to be associated with the Notch pathway while several novel members are revealed by the COCA approach, e.g., transcription factors: TCF4, TBP and PITX2; oncogenes: MYCN, FGFR1 and CCND1.

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