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Table 1 Performance comparison of COCA, PCA-based and variance-based ranking (VR) approaches.

From: Knowledge-guided gene ranking by coordinative component analysis

 

Alpha-factor arrest

CDC15 arrest

CDC28 arrest

 

COCA

PCA-based

VR

COCA

PCA-based

VR

COCA

PCA-based

VR

M/G1

0.8477

0.8277

0.5685

0.9045

0.7594

0.5854

0.7904

0.7661

0.6524

G2

0.8182

0.7172

0.6523

0.8888

0.6979

0.5547

0.8036

0.6767

0.7418

M

0.7731

0.7537

0.6705

0.8873

0.7365

0.5572

0.8448

0.7585

0.5685

G1

0.9123

0.821

0.6611

0.9172

0.7119

0.5521

0.9032

0.7524

0.792

S

0.8763

0.7641

0.7054

0.9478

0.6867

0.6385

0.8532

0.7058

0.799

  1. Area under ROC curves (AUCs) are summarized in the table for ranking cell cycle-related genes in five yeast cell cycle phases, i.e., M/G1, G1, S, G2 and M, respectively