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Table 2 Enriched pathways in the top 500 probe sets ranked by Notch pathway-guided COCA approach

From: Knowledge-guided gene ranking by coordinative component analysis

Pathway Term Count % p-value FDR
Pentose and glucuronate interconversions 8 1.70% 1.64E-06 0.00001847
Notch signaling pathway 8 1.70% 5.65E-04 0.00640122
Porphyrin and chlorophyll metabolism 7 1.49% 6.28E-04 0.00719142
p53 signaling pathway 9 1.91% 9.87E-04 0.01107482
Cell cycle 11 2.34% 0.002362 0.02596788
Starch and sucrose metabolism 8 1.70% 0.002805 0.03161464
Androgen and estrogen metabolism 7 1.49% 0.002846 0.03237976
Polyunsaturated fatty acid biosynthesis 4 0.85% 0.015829 0.1738869
Metabolism of xenobiotics by cytochrome P450 7 1.49% 0.022415 0.2321759
Glycolysis/Gluconeogenesis 6 1.28% 0.024584 0.253719
Fructose and mannose metabolism 5 1.06% 0.054919 0.4893802
Galactose metabolism 4 0.85% 0.075736 0.6119058
PPAR signaling pathway 6 1.28% 0.083934 0.6456008