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Table 5 Components of the Optimal Hyper Plane (OHP) in the SVM analysis

From: Response network analysis of differential gene expression in human epithelial lung cells during avian influenza infections

SVM Components of Significant Genes

Gene

log 2 (Exp Fold)

Ctrl Fold

Exp pval

Ctrl pval

Component

CYR61

-1.51

0.16

2.8 × 10-6

0.31

-.0098

SOCS3

-1.06

-0.07

0.0017

0.39

-0.0095

LOC196752

-0.94

0.11

0.01

0.6

-0.0094

ALDH3B1

-0.86

0.07

0.012

0.9

-0.0094

KLF6

-1.60

0.26

5 × 10-7

0.38

-0.0093

AK024238

-1.32

0.06

7.6 × 10-7

0.39

-0.0093

AA768672

-1.47

-0.30

6.9 × 10-7

0.3

-0.0093

TUBAL3

-1.22

-0.62

0

0.078

-0.0092

THC2348879

-1.22

-0.09

1.4 × 10-6

0.41

-0.0088

THC2313287

-2.74

-0.09

4.1 × 10-13

0.52

-0.0088

IER2

-1.64

0.07

1.8 × 10-6

0.61

-0.0088

ZFP36

-1.74

0.10

3.7 × 10-7

0.67

-0.0086

FOS

-3.47

0.10

1.4 × 10-19

0.6

-0.0086

AHNAK

-0.94

0.15

0.012

0

-0.0085

NFKBIE

1.08

-0.09

0

0.37

0.0085

A_24_P7785

-0.97

-0.12

0.013

0.4

-0.0085

AT_nC_3

-1.32

-0.20

0.0067

0.78

-0.0084

CTGF

-1.43

0.03

2 × 10-8

0.37

-0.0084

AT_ssH_RR_5

-1.56

-0.14

1.3 × 10-6

0.26

-0.0083

AF159295

-1.89

0.26

2.5 × 10-7

0.3

-0.0083

JUN

-1.74

-0.20

7.3 × 10-7

0.26

-0.0083

FOSB

-2.18

0.26

1.2 × 10-9

0.58

-0.0082

SYT12

0.88

-0.09

0.012

0.93

0.0082

AK022038

-0.89

0.26

0.013

0.35

-0.0082

EGR1

-3.18

0.21

1.9 × 10-18

0.44

0.0081

A_24_P494658

-0.86

0.08

0.022

0.25

-0.008

HP1BP3

-1.00

-0.04

0.0033

0.62

-0.008

ENST00000380874

-0.97

-0.42

0.0033

0.21

-0.0079

TRAF2

-0.77

-0.17

0.025

0.31

0.0078

DUSP1

-1.79

0.43

2.2 × 10-7

0.27

-0.0078

RELB

1.14

0.15

0

0.29

0.0078

ABCC3

1.38

0.03

1.9 × 10-6

0.23

0.0078

FOXC1

-1.15

0.01

0

0.72

-0.0077

SFRS5

-1.47

0.41

7.1 × 10-9

0.31

-0.0077

G0S2

2.38

0.42

1.5 × 10-8

0.22

0.0076

  1. The components of the OHP in the SVM analysis are displayed along with the average fold change of the gene in the H5N1 data and control data, and the average p-values in the H5N1 and control data. The length of each component is also given. A negative component to the vector normal to the OHP indicates a decrease in the fold change in gene expression from the control to the H5N1 exposures while a positive component indicates an increase in the differential expression from control to H5N1.