APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility

Table 5 Evaluation of hot spot prediction using the majority voting method based on the independent test set

Classifier number	Specificity	Recall	Precision	Accuracy	F1	TP	TN	FP	FN
9 (all)	0.67	0.69	0.48	0.68	0.57	27	59	29	12
7 (F1 > 0.50)	0.68	0.69	0.49	0.69	0.58	27	60	28	12
3 (F1 > 0.59)	0.76	0.72	0.57	0.75	0.64	28	67	21	11

ISSN: 1471-2105