Figure 5

The extracted features characterize well-known leukemia subtypes. Representation of the samples from the validation set by their coordinates in the first two pairs of features extracted from the tuning set using regularized dual CCA, with regularization parameters τ _x = 0.9, τ _y = 0.3 (left panel), and PCA+CCA (right panel). We show the representations with respect to both the copy number features and the gene expression features in a superimposed way, where each sample is represented by two markers. The filled markers represent the coordinates in the features extracted from the copy number variables, and the open markers represent coordinates in the features extracted from the gene expression variables. Samples with different leukemia subtypes are shown with different colors. The first feature pair distinguishes the HD50 group from the rest, while the second feature pair represents the characteristics of the samples from the E2A/PBX1 group.