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Table 4 Results for the same quantities shown in Table 3, except only for the 27 transmembrane helix pair structures that have at least 15 inter-helix residue contacts

From: Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design

Include homolog sequences?

Include depth-dependent score

Percentile rank of native sequence

Median Percentile Rank

  

1%

5%

10%

 

No

No

9 (33%)

13 (48%)

20 (74%)

6.7%

No

Yes

9 (33%)

15 (56%)

20 (74%)

3.6%

Yes

No

10 (37%)

13 (48%)

20 (74%)

5.3%

Yes

Yes

11 (41%)

16 (59%)

22 (81%)

2.3%

  1. Comparison with the results in Table 3 show that the threading accuracy is higher for this subset of helix pairs with large interfaces, because of the stronger signal resulting from more inter-helix residue contacts.