Figure 5From: Systematic calibration of a cell signaling network modelDeterministic and stochastic sampling of 2D parameter space. Plots show the initial and final parameter value combinations on the parameter space for k8 and k9 during global optimization process by (a) deterministic multi-start method and (b) evolutionary strategy using stochastic ranking. Starting points are indicated by red circles (top) and endpoints by blue triangles (bottom). Common contour of all sections represents the surface of the objective function.Back to article page