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Table 3 Comparison of estimation performance by different optimization algorithms

From: Systematic calibration of a cell signaling network model

  Local optimization Multi-start of local optimization SRES(G = 33) SRES (G = 300) SRES (G = 33) & local optimization
Number of surveyed parameter combinations 1 6561 6600 60000 6600
CPU time ~1 minute 2600 hours 2 hours 18 hours 2 hours
Objective function 45.04 0.2447 3.546 1.739 0.2679
  1. SRES, Evolutionary Strategy using Stochastic Ranking; G, generation number of evolution.