Skip to main content

Table 3 Comparison of estimation performance by different optimization algorithms

From: Systematic calibration of a cell signaling network model

 

Local optimization

Multi-start of local optimization

SRES†(G‡ = 33)

SRES (G = 300)

SRES (G = 33) & local optimization

Number of surveyed parameter combinations

1

6561

6600

60000

6600

CPU time

~1 minute

2600 hours

2 hours

18 hours

2 hours

Objective function

45.04

0.2447

3.546

1.739

0.2679

  1. † SRES, Evolutionary Strategy using Stochastic Ranking;‡ G, generation number of evolution.