Figure 6

Sensitivity versus Specificity Performance on Small and Large Families from Pfam 22.0. The performances of HMMER2, HMMER3, SAM, PSI-BLAST, sub-HMM-HMMER2 and sub-HMM-HMMER3 on the Pfam 22.0 data set are compared in the form of ROC curves (compare Figure 5). The first test (a) considers smaller families with 10 to 100 members, whereas the second one (b) considers large families with more than 100 members.