Predicting conserved protein motifs with Sub-HMMs

BMC Bioinformatics

Table 2 PROSITE Comparisons.

Overlap	Sub-HMMs	PROSITE	TP	TPR
10%	1,054	937	562	0.58
25%	1,023	932	558	0.58
50%	965	912	549	0.57
75%	849	827	495	0.51
90%	720	716	423	0.44
100%	620	624	366	0.38

The numbers of sub-HMMs are listed that overlapped with PROSITE motifs. The first column provides the relative overlap among the two feature types. The second and third columns contain the number of overlapping sub-HMMs and PROSITE motifs, respectively. The details of the filter settings used in these comparisons is given in the Result and Discussion section. The column TP contains the number of true positives that we identified out of the 958 PROSITE families annotated by Pfam 22.0. The last column TPR gives the corresponding true positive rate.

ISSN: 1471-2105