Content of BiGG. The three largest reconstructions in BiGG are E. coli i AF1260, S. cerevisiae i ND750, and H. sapiens Recon 1. Their shared content can be queried with BiGG: a) The shared reactions. Non-exchange reactions are shown in parenthesis. b) The number of shared metabolites. c) The distribution of reactions and metabolites across all seven reconstructions.