Figure 4
Obtaining a consensus metabolite feature. Examples of enabled technologies. (A) MetMask makes it easy to cross-reference identifiers used in different metabolomics platforms. Once this has been done, features representing the same metabolite can be summarized using, e.g., principal component analysis to obtain a consensus data set. Here, an example is shown where the features from CE-MS and GC-MS that represent alanine are replaced by PC1. (B) MetMask can link unified identifiers to annotation databases such as PlantCyc, thereby allowing for contextual interpretation such as metabolite set enrichment analysis. The boxplot shows that the log fold changes between red and green tomatoes are higher among the nucleotide synthesis related metabolites than the other metabolites.