From: Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
 | (-)non-obligate interactions | obligate interactions(+) | |||||
---|---|---|---|---|---|---|---|
support level | range of support ratios | ||||||
 | -INF | -3 | -2 | 1 | 2 | > = 3 | INF |
 | -INF | (-3.5,-2.5] | (-2.5,-1.5] | (-1.5,1.5) | [1.5,2.5) | [2.5,5.5) | INF |
2 | 223 | 0 | 0 | 436 | 0 | 0 | 523 |
3 | 17 | 0 | 38 | 0 | 76 | 0 | 90 |
4 | 2 | 5 | 0 | 6 | 0 | 12 | 19 |
> = 5 | 2 | 0 | 1 | 0 | 3 | 11 | 9 |
Total | 244 | 5 | 39 | 442 | 79 | 23 | 641 |