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Table 2 Mean and standard deviation of the (absolute) Student's t statistics to test the null hypothesis of equal means in two flanking PCN regions based on heterozygous SNPs only.

From: TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays

Heterozygous SNPs only
Signals Genotypes N/G G/L N/D D/L N/N
Raw DH (ρ T ) Birdseed 7.17 ± 1.13 27.79 ± 1.93 24.22 ± 1.35 8.88 ± 1.04 0.78 ± 0.64
Normalized DH () Birdseed 21.00 ± 1.45 39.42 ± 2.54 40.22 ± 2.36 11.04 ± 1.13 0.74 ± 0.59
Normalized DH () naive 18.61 ± 1.39 33.38 ± 2.31 35.40 ± 2.07 9.40 ± 1.01 1.06 ± 0.68
TCN (C T ) Birdseed 16.43 ± 1.05 18.55 ± 1.26 25.69 ± 1.32 20.57 ± 1.23 2.19 ± 0.99
  1. Greater mean values correspond to greater power to detect a change point. Raw (top line) and TumorBoost-normalized (second and third line) DHs, and TCNs (bottom line).