Figure 4From: Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation dataA simulation study of the proposed model. (A) Traditional methods estimate the locations of origins from the peaks of T50 timing profile (shown in blue); while the proposed method estimates locations of origins from the regional firing efficiency curve (shown in red). (B) A comparison between the true value and estimated value of locations of origins, firing efficiency, firing staring time (T s ) and ending time (T e ).Back to article page