Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data

BMC Bioinformatics

Table 4 Inhibition parameters for independent combinations of targeted genes.

Parameters for each of four gene combinations	Antisense inhibition parameter P (%)
CRAF1 minus average	2.20 ± 2.36
BCL2 minus average	-4.54 ± 1.86
AKT2 minus average	7.53 ± 4.37
PKC-α minus average	-5.20 ± 2.83

Values are the differences from the average of the four gene parameters in Table 1. Any set of three of the four parameters is an independent set. The fourth is a dependent parameter, since it is a linear combination (i.e. the negative sum) of the three parameters chosen to be independent. Percent standard errors were derived from the SVD variance-covariance matrix.

ISSN: 1471-2105