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Figure 2 | BMC Bioinformatics

Figure 2

From: The Protein-DNA Interface database

Figure 2

Protein-protein interaction modes with DNA. Three modes of protein-protein interaction with DNA are defined, according to the direction and the axis of the DNA helix. (A) Mode 1, the direction of the protein interaction and the double helix axis are orthogonal. (B) Mode 2, the direction of the interaction is parallel to the double helix axis. (C) Mode 3, both previous modes are observed at the same time. In the Mode 3 example, the histone core shown is the only instance of this case in the current version of the database. The histone core presents a set of proteins interacting with each other, thus making up a continuous interface with DNA. Additionally, a Mode 0 to assign those interfaces with only one protein has also been defined (not shown).

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