Figure 4
Degree distribution of the functional similarity networks. The similarity threshold value of 0.95 are used to connect edges. The X-axis is the number of interactions, k (the degree of interactions) and the Y-axis is the probability of proteins with a certain number of interactions, P(k). Both axes are log scaled. The dotted line is fit to the data to compute the degree exponent, γ, in the power-law degree distribution: P(k)~ k-γ. A, E. coli; B, S. cerevisiae; C, P. falciparum. From left to right, the BP-score, CC-score, MF-score, and the funSim score. The degree exponent values are shown in Table 3. The R2value of the fitted line to each distribution is as follows. E. coli: 0.579 (BP), 0.144 (CC), 0.472 (MF), 0.872 (funSim); S. cerevisiae: 0.585 (BP), 0.481 (CC), 0.505 (MF), 0.798 (funSim); P. falciparum: 0.466 (BP), 0.345 (CC), 0.068 (MF), 0.825 (funSim).