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Figure 3 | BMC Bioinformatics

Figure 3

From: sdef: an R package to synthesize lists of significant features in related experiments

Figure 3

Posterior mean of R ( h ) and 95% credibility interval (two lists). Plot for the Bayesian estimate of R(h) and its credibility interval (baymod function) on the mice data described in the section "Illustrative analysis: Type 2 diabetes susceptibility in mice" (two lists). The p-values are on the x-axis; the left y-axis shows R(h), while the right y-axis shows the number of genes in common for some values of R(h). A dotted line is drawn for the values of R(h max ) and R(h2 ). R(h max ) returns a list of 68 features in common, the same as in Figure 1. R(h2 ) corresponds to a larger list of 104 features associated with a threshold p-value h2 = 0.04. For this p-value the Bayesian model assesses that the common list of 104 features contains at least twice more genes than expected by chance.

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