Figure 5
From: Prediction of epigenetically regulated genes in breast cancer cell lines
Subnetwork enrichment (Jun/Fos). Jun/Fos complex has been shown to be a common regulator for 13 of the predicted epigenetic biomarkers. Jun/Fos' subnetwork's statistical significance (p-value) is 1.68E-06, as shown in Table 3, row 2. Together with the AP1 transcription factor, Jun and Fos drive expression of a number of genes necessary for cell cycle progression