Figure 7

A LucidDraw layout of a large network with 677 nodes. The network consists of 7 functional subsystems and some unassigned reactions of P.aeruginosa PAO1 with totally 677 nodes. Reaction nodes of the same functional subsystems are drawn in identical shapes and colors: red square = virulence factor synthesis; dark gray round rectangle = central metabolism; light blue round rectangle = sulfur metabolism; green rectangle = lipid synthesis; dark blue rectangle = ethanol/pyruvate metabolism; red diamond = cell wall/LPS synthesis; dark blue diamond = tRNA synthetases; yellow circle = unassigned reactions and dark blue ellipse = metabolites. We added an extra positive value (= 15) to the weights w _ij of any two reactions which belong to the virulence factor synthesis. The details of rectangular area A are shown in Figure 8. The area B is mainly occupied by virulence factor synthesis functional subsystem.