Table 1 Designations and descriptions of kinases whose substrates were included into the training set
Kinase type | Description | Lmin | Lmax |
|---|---|---|---|
ABL1 | Proto-oncogene tyrosine-protein kinase | 178 | 1271 |
ATM | Ataxia telangiectasia mutated | 118 | 3056 |
AURORA_A | Serine/threonine-protein kinase 6 (STK6) | 136 | 1863 |
AURORA_B | Serine/threonine-protein kinase 12 (AURKB) | 136 | 923 |
CAM_KII_group | Calcium/calmodulin-dependent protein kinase II | 52 | 5037 |
CAM_KII_alpha | Calcium/calmodulin-dependent protein kinase II alpha | 52 | 4967 |
CDK1 | Cell division control protein 2 homolog (Cyclin-dependent kinase 1) | 107 | 4684 |
CDK2 | Cell division protein kinase 2 | 119 | 1971 |
CDKgroup | Cyclin-dependent kinases | 149 | 1863 |
CK1alpha | Casein kinase 1, alpha | 140 | 911 |
CK1group | Casein kinases 1 | 195 | 2843 |
CK2group | Casein kinase 2 | 98 | 2346 |
DNA_PK | DNA-dependent protein kinase catalytic subunit | 270 | 4128 |
EGFR | Epidermal growth factor receptor (Receptor tyrosine-protein kinase ErbB-1) | 76 | 1291 |
ERK2 | Mitogen-activated protein kinase 1 | 196 | 2225 |
ERK1 | Mitogen-activated protein kinase 3 | 168 | 2749 |
FYN | Proto-oncogene tyrosine-protein kinase Fyn | 164 | 2758 |
GSK3beta | Glycogen synthase kinase 3 beta | 164 | 2470 |
GSKgroup | Glycogen synthase kinases 3 | 157 | 1914 |
INS_R | Insulin receptor | 132 | 1382 |
JNK1 | c-Jun N-terminal kinase 1 | 196 | 1242 |
JNK2 | c-Jun N-terminal kinase 2 | 196 | 1075 |
LCK | Lymphocyte-specific protein tyrosine kinase | 220 | 2472 |
LKB1 | Serine/threonine kinase 11 (LKB1) | 433 | 1263 |
LYN | Tyrosine-protein kinase Lyn | 202 | 1827 |
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 168 | 1807 |
MAPKgroup | P38, JNK and ERK | 136 | 1914 |
PAK1 | Serine/threonine-protein kinase PAK1 | 89 | 2647 |
PDK-1 | 3-phosphoinositide dependent protein kinase 1 | 268 | 1374 |
PKAalpha | Protein kinase, cAMP-dependent, catalytic, alpha | 52 | 2749 |
PKAgroup | cAMP-dependent protein kinase | 30 | 5037 |
PKBgroup | Protein kinases B | 130 | 5890 |
PKCalpha | Protein kinase C, alpha type | 72 | 2441 |
PKCbeta | Protein kinase C, beta 1 | 149 | 1531 |
PKCdelta | Protein kinase C, delta type | 187 | 2414 |
PKCgroup | Protein kinase | 30 | 2442 |
PKCzeta | Protein kinase C, zeta type | 147 | 1242 |
PKGgroup | cGMP-dependent protein kinases | 90 | 5037 |
PLK1 | Polo like kinase 1 | 163 | 3418 |
ROCKgroup | Rho-associated, coiled-coil containing protein kinases | 309 | 737 |
RSKgroup | Ribosomal protein S6 kinases | 198 | 2647 |
SGKgroup | Serum/glucocorticoid regulated kinase | 341 | 3144 |
SRC | Proto-oncogene tyrosine-protein kinase Src | 101 | 4544 |
SYK | Tyrosine-protein kinase SYK (Spleen tyrosine kinase). | 113 | 1290 |
P38alpha | mitogen-activated protein kinase 14 | 168 | 902 |