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Figure 1 | BMC Bioinformatics

Figure 1

From: A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization

Figure 1

Phylogenetic tree of human Class A GPCRs based on sequence information (44 residues of the GSK set). Human Class A GPCRs are clustered based on the 44 ligand-binding residues as defined in the GSK set. Subfamilies are color-coded according to ligand type whereby the broad ligand types applied by Gloriam et al. [17] were used. red - receptor with aminergic ligands; pink - peptide ligands; green - lipid ligands; dark blue - purinergic P2Y ligands; light blue - adenosine ligands; brown - melatonin ligands.

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BMC Bioinformatics

ISSN: 1471-2105

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