Overview of WATERS. Schema of WATERS where white boxes indicate "behind the scenes" analyses that are performed in WATERS. Quality control files are generated for white boxes, but not otherwise routinely analyzed. Black arrows indicate that metadata (e.g., sample type) has been overlaid on the data for downstream interpretation. Colored boxes indicate different types of results files that are generated for the user for further use and biological interpretation. Colors indicate different types of WATERS actors from Fig. 2 which were used: green, Diversity metrics, WriteGraphCoordinates, Diversity graphs; blue, Taxonomy, BuildTree, Rename Trees, Save Trees; CreateUnifrac; yellow, CreateOtuTable, CreateCytoscape, CreateOTUFile; white, remaining unnamed actors.